{
  "title": "CardioMetaIQ v4.8 website-export numerical audit",
  "date": "2026-10-04",
  "scope": "Numerical reproduction of supplied frozen references; not independent clinical validation.",
  "verifiedReleaseFiles": 270,
  "displayedDatasetSHA256": "c709980036ceeda9d6e9e81bfb719338a6789a10f6565aa3966db94e2db1a23c",
  "endpointReproductionChecks": [
    {
      "key": "weight",
      "model": -11.546683700538248,
      "reference": -11.546683700538248,
      "error": 0.0,
      "passed": true
    },
    {
      "key": "kccq",
      "model": 7.8,
      "reference": 7.8,
      "error": 0.0,
      "passed": true
    },
    {
      "key": "6mwd",
      "model": 20.3,
      "reference": 20.3,
      "error": 0.0,
      "passed": true
    },
    {
      "key": "crp",
      "model": 0.7266777844011283,
      "reference": 0.7266777844011282,
      "error": 1.1102230246251565e-16,
      "passed": true
    }
  ],
  "maximumScaledHalfStepDifference": 1.1737277951389675e-05,
  "fullReleaseRerun": false,
  "limitations": [
    "The reference values are frozen model outputs, not independent patient observations.",
    "KCCQ-CSS and 6-minute walk differences are calibration anchors.",
    "The hs-CRP ratio of approximately 0.727 is slightly outside the supplied published interval 0.51\u20130.72.",
    "Some baseline fields are imputed and renal assumptions remain unanchored.",
    "The analytic virtual-trial demo is separate from these stored trajectories."
  ],
  "trialPublication": {
    "date": "2023-08-25",
    "url": "https://www.nejm.org/doi/abs/10.1056/NEJMoa2306963"
  }
}